Blar i forfatter "Sunyer, J Oriol"

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    • Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression 

      Jenberie, Shiferaw; Thim, Hanna Leena; Sunyer, J Oriol; Skjødt, Karsten; Jensen, Ingvill; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-23)
      While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnetic sorted IgM<sup>+</sup> cells. Of the two receptors recognizing CpG in teleosts, <i>tlr9</i> was the ...